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Heart and Metabolic Health

Lipoprotein(a): The Blood Test That Can Change Your Cardiovascular Risk

Updated

Lipoprotein(a) scientific diagram with labels

This blood test can significantly change how we assess cardiovascular risk — and many patients have never had it measured.

Executive Medicine editorial graphic: Heart and Metabolic Health

It’s called Lipoprotein(a), or Lp(a), and most standard cholesterol panels don’t include it.

Why this matters

You can eat well, exercise regularly, and have “normal” cholesterol levels — and still carry elevated cardiovascular risk.

Lp(a) is largely genetic, meaning lifestyle changes alone may not fully explain your risk profile.

What is Lipoprotein(a)?

Lipoprotein(a) is a cholesterol-related particle linked to cardiovascular disease. Unlike standard cholesterol markers, it is largely genetically determined.

You are born with your level, it remains relatively stable over time, and in most cases only needs to be measured once.

Why it changes management

Elevated Lp(a), seen in around 1 in 5 people, can significantly influence how cardiovascular risk is interpreted.

  • Amplifies the impact of LDL cholesterol
  • Accelerates atherosclerosis
  • Increases the risk of heart attack and stroke

This can change treatment targets and determine whether more aggressive prevention is appropriate.

You can learn more about our approach to testing here: Blood tests Sydney

Dr Georgia Wyatt, Medical Director, Executive Medicine
About the author

Dr Georgia Wyatt

Medical Director, Executive Medicine

Dr Georgia Wyatt is a general practitioner with a background in medical science, tropical medicine and preventative health. As Medical Director of Executive Medicine, she takes a comprehensive approach to early detection, risk assessment and long-term health planning.

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